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Nonapeptide-3

Nonapeptide-3 [Myristoyl Nonapeptide-3] is a restorative, retinol-esque ingredient used for the first time in haircare by isima to promote a healthy-feeling scalp.

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Nonapeptide-3 is a peptide consisting of 9 amino-acids [hence “nona”]. Typically used in skincare formulations [think serums or creams] as a retinoid-alternative, it’s embraced by consumers who are seeking retinol-like benefits without the irritation of Vitamin A.

Its mechanism of action mimics the activity of retinol. We’ve scientifically proven that Nonapeptide-3 can promote hair growth on human hair follicles, highlighting its potential in haircare formulations.

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A weak or unhealthy scalp can negatively impact hair growth and retention. When the scalp is compromised and cannot properly support hair follicles and the growth process, issues like increased breakage, thinning and even hair loss can occur.

Nonapeptide-3 helps reinforce the scalp’s resilience to provide a better foundation for healthier, stronger hair, thanks to its demonstrated mechanisms of action, including:

  • Promoting cellular turnover 

  • Increasing the epidermis thickness 

  • Boosting collagen production  

By supporting scalp health—improving moisture, soothing skin and maintaining a balanced microbiome—our Iconic Densifying Scalp Serum with Nonapeptide-3 helps promote the ideal foundation for fuller, stronger, denser hair with time.